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If you have any further questions, please consult a treatment specialist today. Below we look at some of the long term meth effects and what you can expect with continued use. For this reason, users should seek professional help from a treatment center when ending addiction meth.įurthermore, users should also get medical help once they start experiencing side effects of meth, as long-term use can be fatal. Quitting the addiction is extremely challenging and can often lead to multiple relapses. One of the most common long-term meth effects is an addiction. Long-term addiction to methamphetamines (meth) can lead to terminal severe health problems.